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Abstract:
OBJECTIVES:Although it has been well-established that menopause causes a shift in body fat, there has been no study conducted yet to examine the best obesity parameters to predict the risk of nonalcoholic fatty liver disease (NAFLD) in this population. Thus, the aim of this study was to clarify the superiority among various obesity indices such as body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) for predicting NAFLD in pre- and postmenopausal women. METHODS:This cross-sectional analysis included 620 healthy women (318 premenopausal and 302 postmenopausal women) between 20 and 80 years of age recruited from the Health Promotion Center of Korea University Guro Hospital. NAFLD was diagnosed by abdominal ultrasonography. RESULTS:In premenopausal women, there were no statistical differences in the area under the curve values among the three obesity indices, whereas, in postmenopausal women, the area under the curve value of WHR was significantly larger than those of either BMI (difference between area: 0.102, 95% confidence interval: 0.031, 0.173) or WC (difference between area: 0.064, 95% confidence interval: 0.018-0.109). Furthermore, in postmenopausal women, the combination of WHR with BMI or WC significantly increased predictive power of NAFLD when compared to using BMI or WC alone. The optimal cutoff values for BMI, WC, and WHR for detecting NAFLD were 23.9 kg/m, 69 cm, and 0.81 in premenopausal women and 22.9 kg/m, 74 cm, and 0.86 in postmenopausal women, respectively. CONCLUSIONS:In premenopausal women, BMI, WC, and WHR hold similar potential in predicting the risk of NAFLD, whereas, in postmenopausal women, WHR is the most useful discriminative indicator for NAFLD. Women's optimal cutoff values for NAFLD were different according to menopausal status.
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最新影响因子:3.31 | 期刊ISSN:1072-3714 | CiteScore: |
出版周期:Bimonthly | 是否OA:YES | 出版年份:1994 |
期刊官方网址:http://www.menopause.org/publications/professional-publications/menopause-journal-contents/menopause
自引率:18.70% | 研究方向:医学-妇产科学 |
出版地区:UNITED STATES |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Menopause: The Journal of The North American Menopause Society publishes articles of importance in this rapidly expanding area of interest to specialists, general practitioners, nurses, and social workers. It features peer-reviewed, original research papers and review articles related to menopause, hormone replacement therapy, nonhormone and hormone-related aging factors in women, cardiovascular disease in women, osteoporosis, breast cancer and other female cancers, and primary-preventive health care for women in the perimenopausal period.
更年期:《北美更年期协会杂志》发表了许多重要的文章,引起了专家、全科医生、护士和社会工作者的兴趣。它的特点是同行评审,原始的研究论文和评论文章有关更年期,激素替代疗法,非激素和激素相关的老化因素的妇女,心血管疾病的妇女,骨质疏松症,乳腺癌和其他女性癌症,以及初级预防保健妇女在围绝经期。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
OBSTETRICS & GYNECOLOGY(产科医学和妇科医学) 3区 |
24/82 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
161 | 150 | 11 |
引文计数(2018)
文献(2015-2017)
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研究方向:menopause
接受率: 中等(50%命中)
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接受率: 中等(50%命中)
影响因子:2.183
ISSN:1538-9588
研究方向:PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
影响因子:4.814
ISSN:0049-4488
研究方向:工程技术-工程:土木
影响因子:7.632
ISSN:0191-2615
研究方向:工程技术-工程:土木
影响因子:10.047
ISSN:1366-5545
研究方向:工程技术-工程:土木
影响因子:4.898
ISSN:0041-1655
研究方向:工程技术-运筹学与管理科学
影响因子:3.817
ISSN:1867-0717
研究方向:-
影响因子:3.277
ISSN:2324-9935
研究方向:TRANSPORTATION SCIENCE & TECHNOLOGY-
影响因子:3.41
ISSN:2168-0566
研究方向:TRANSPORTATION SCIENCE & TECHNOLOGY-
影响因子:6.615
ISSN:0965-8564
研究方向:工程技术-运输科技
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