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Abstract:
To investigate the association between neonatal complications and neurophysiological development in twins at 18 and 48-60 months of age. This was a secondary analysis of 841 Danish mono- and dichorionic diamniotic twins from a randomized controlled trial (PREDICT study), which included an assessment of the twin's neurophysiological development using the Ages and Stages Questionnaire (ASQ) that had been filled out by the parents at 18 and 48 or 60 months. The correlation within twin pairs was accounted for by the method of generalized estimating equation. Models were adjusted for maternal educational score and gestational age at delivery. ASQ data were available for 823 children at 18 months and 425 children at 48 or 60 months. Low maternal educational score and preterm delivery <34 weeks were associated with a lower ASQ score at 48-60 months (-15.4 points (95%CI -26.4; -4.5) and -13.2 points (95%CI -23.8; -2.5), respectively). Neonatal sepsis and a compound of intraventricular hemorrhage, retinopathy of prematurity and necrotizing enterocolitis (IVH/ROP/NEC) were associated with lower ASQ score at 18 months (-15.3 points (95%CI -28.1; -2.5) and -30.8 points (95%CI -59.5; -2.1), respectively). Children with IVH/ROP/NEC had a lower ASQ score at 48-60 months (-34.2 points (95%CI -67.9; -0.6)). The associations were not specific to only one ASQ domain. Several neonatal complications are associated with poorer neurophysiological development in twins during childhood, even after adjustment for gestational age at delivery.
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最新影响因子:2.323 | 期刊ISSN:1476-7058 | CiteScore:N/A |
出版周期:Monthly | 是否OA:YES | 出版年份:2002 |
自引率:9.00% | 研究方向:医学-妇产科学 |
出版地区:ENGLAND |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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大类(学科) | 小类(学科) | 学科排名 |
医学 |
OBSTETRICS & GYNECOLOGY (妇产科学) 4区 |
62/82 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
539 | 498 | 41 |
引文计数(2018)
文献(2015-2017)
N/A次引用
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序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Obstetrics and Gynecology
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研究方向:胎儿医学
审稿时间: 3个月内 接受率: 一般容易(75%命中)
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研究方向:meta分析
审稿时间: 6个月内 接受率: 一般容易(75%命中)
影响因子:2.473
ISSN:1362-4393
研究方向:医学-临床神经学
影响因子:1.14
ISSN:1443-9646
研究方向:CLINICAL NEUROLOGY-NEUROSCIENCES
影响因子:1.986
ISSN:1053-8135
研究方向:CLINICAL NEUROLOGY-REHABILITATION
影响因子:1.907
ISSN:1751-8423
研究方向:CLINICAL NEUROLOGY-PEDIATRICS
影响因子:3.117
ISSN:0885-9701
研究方向:医学-康复医学
影响因子:4.895
ISSN:1545-9683
研究方向:医学-康复医学
影响因子:4.655
ISSN:1557-0576
研究方向:CLINICAL NEUROLOGY-REHABILITATION
影响因子:1.452
ISSN:0898-5669
研究方向:PEDIATRICS-REHABILITATION
影响因子:2.297
ISSN:0194-2638
研究方向:PEDIATRICS-REHABILITATION
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