Pre-labor screening at term using the cerebroplacental ratio and placental growth factor: a pragmatic randomized open label Phase 2 trial.

Abstract:
BACKGROUND AND OBJECTIVE:In some women placental function may not be adequate to meet fetal growth requirements in late pregnancy or the additional demands during labor thus predisposing these infants to intrapartum fetal compromise (IFC) and subsequent serious morbidity and mortality. The objective of this study was to determine if the introduction of a pre-labor screening test at term combining the cerebroplacental ratio and maternal placental growth factor level would result in a reduction in a composite of adverse outcomes. STUDY DESIGN:Single-site, non-blinded, randomized controlled trial conducted at a tertiary hospital in Brisbane, Australia. Eligible women were randomized to either receive the screening test performed between 37-38 weeks or routine obstetric care. Screen positive women were offered induction of labor. The primary outcome was a composite of: emergency cesarean for non-reassuring fetal status (fetal distress) or severe neonatal acidosis or low Apgar score or stillbirth or neonatal death. RESULTS:Women were recruited and randomized (n=501) between April 2017 to January 2019. 63/249 (25·3%) of the screened group compared to 56/252 (22·2%) of the control group experienced the primary outcome (Relative Risk (RR) = 1·14 [95% CI 0·83 - 1·56]; p = 0·418). Women who screened positive were more likely to require operative delivery for fetal distress, have meconium stained liquor, pathological FHR abnormalities and have infants with lower birth weight compared to women that screened negative. CONCLUSION:The introduction of this test did not result in improvements in intrapartum intervention rates or neonatal outcomes. However, it did show discriminatory potential and future research should focus on refining the thresholds used.
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AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
AM J OBSTET GYNECOL
最新影响因子:10.693 | 期刊ISSN:0002-9378 | CiteScore:3.5 |
出版周期:Monthly | 是否OA:YES | 出版年份:1920 |
期刊官方网址:http://www.ajog.org/
自引率:11.90% | 研究方向:医学-妇产科学 |
出版地区:UNITED STATES |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY 期刊简介
英文简介:
The American Journal of Obstetrics and Gynecology, “The Gray Journal”, covers the full spectrum of Obstetrics and Gynecology. The aim of the Journal is to publish original research (clinical and translational), reviews, opinions, video clips, podcasts and interviews that will have an impact on the understanding of health and disease and that has the potential to change the practice of women's health care. An important focus is the diagnosis, treatment, prediction and prevention of obstetrical and gynecological disorders. The Journal also publishes work on the biology of reproduction, and content which provides insight into the physiology and mechanisms of obstetrical and gynecological diseases.
中文简介:(来自Google、百度翻译)
美国妇产科杂志,“灰色杂志”,涵盖了妇产科的所有领域。该杂志的目的是发表原创研究(临床和翻译)、评论、意见、视频剪辑、播客和访谈,这些将对健康和疾病的理解产生影响,并有可能改变妇女保健的做法。妇产科疾病的诊断、治疗、预测和预防是一个重要的研究重点。该杂志还出版了生殖生物学方面的著作,内容涉及妇产科疾病的生理学和机制。 好处的作者
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY 期刊中科院评价数据
最新中科院分区
大类(学科) | 小类(学科) | 学科排名 |
医学 |
OBSTETRICS & GYNECOLOGY(产科医学和妇科医学) 1区 |
2/82 |
最新公布的期刊年发文量
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
343 | 310 | 33 |
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AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY 期刊CiteScore评价数据
最新CiteScore值
引文计数(2018)
文献(2015-2017)
6254次引用
1788篇文献
CiteScore排名
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Obstetrics and Gynecology
|
#5/168
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liting7111
研究方向:妇产科
写了篇流行病方向文章,同门的投稿都是一个月就审回,我两个月才审回,5个审稿人给了拒绝,但是可以修改后重投,大修再投两个月还是被拒了。2020-06-11 -
liting7111
研究方向:妇产科
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9月1号投稿,10月7号通知拒稿。审稿速度块,审稿人意见也很有价值。2020-04-12 -
liting7111
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审稿一个半月拒稿,不怎么好中,接受率20%2020-03-18 -
liting7111
研究方向:临床 流行病学 妇科学
审稿时间: 2个月内 接受率: 比较困难(25%命中)
投稿后竟然看不到状态,不过两个月后拒稿了,审稿人意见挺不错的。2020-02-15 -
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杂志收不收综述文章?2019-08-22 -
liting7111
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审稿时间: 2个月内 接受率: 比较困难(25%命中)
之前投稿gynecology oncology被拒,按照意见修改后去年12月投稿,两个月修回,小修之后四个月接收,4月底在线,杂志还是偏临床。2019-05-12
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