Maternal exposure to a high-fat diet showed unfavorable effects on the body weight, apoptosis and morphology of cardiac myocytes in offspring

Abstract:
Objective The study intends to explore the functions of maternal high-fat diet exposure on progeny weight and heart. Methods Sprague–Dawley (SD) rats, fed on a high-fat diet, were used to establish a model of weight gain before and during pregnancy. The body and cardiac weight of neonatal, 1-month- and 3-month-old rats were measured. The morphology of myocardial cells was observed by hemotoxylin and eosin (H&E) staining. The expression of caspase-3, 8, 9 was measured by qRT-PCR and western blot. Results Normal pregnant rats, fed on a high-fat diet throughout pregnancy, had a significant increase in body and cardiac weight of their neonates, and more fat deposition in myocardial cells and an increased expression of caspase-3, 8, 9, compared with that of the normal pregnant rats + normal diet group. These phenomena were relieved through later diet control. Pregnant rats, which fed on a high-fat diet throughout pregnancy, showed more adverse effects on neonatal body and cardiac weight, myocardial cell fat deposition, and the expression of caspase-3, 8, 9, compared with pregnant rats exposed to high-fat diet + normal diet and pregnant rats exposed to high-fat diet + normal diet + exercise. These phenomena cannot be fully restored via controlling later diet. Conclusions Our results stated that a proper diet before and during pregnancy was important for the cardiac health of offspring.
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ARCHIVES OF GYNECOLOGY AND OBSTETRICS
ARCH GYNECOL OBSTET
最新影响因子:2.493 | 期刊ISSN:0932-0067 | CiteScore:1.97 |
出版周期:Bimonthly | 是否OA:YES | 出版年份:1987 |
期刊官方网址:http://www.springer.com/medicine/gynecology/journal/404
自引率:17.90% | 研究方向:医学-妇产科学 |
出版地区:GERMANY |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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ARCHIVES OF GYNECOLOGY AND OBSTETRICS 期刊简介
英文简介:
The Archives of Gynecology and Obstetrics was founded in 1870 as "Archiv für Gynaekologie" and has a long and outstanding tradition. Since 1922 the journal has been the Organ of the Deutsche Gesellschaft für Gynäkologie und Geburtshilfe and publishes the abstracts and proceedings of their bi-annual meetings. The Archives of Gynecology and Obstetrics is circulated in over 40 countries world wide and is indexed in Current Contents and Index Medicus. The Archives of Gynecology and Obstetrics publishes " invited and submitted reviews " original articles about clinical topics and basic Research " case reports and " preliminary communications from all subspecialities in Gynecology and Obstetrics. All papers are peer-reviewed and published as quickly as possible. The Archives of Gynecology and Obstetrics publishes -Editorials -Letters to the Editor -News and Views -Reviews -Original articles about clinical topics and basic research in the categories: Maternal Fetal Medicine General Gyneocology Gynecologic Oncology Gynecologic Endocrinology and Reproductive Medicine Urogynecology -Position Statements and Guidelines -Correspondence -Images in Obstetrics and Gynecology -Erratum -Abstracts from all subspecialties in Gynecology and Obstetrics. All papers are peer-reviewed and published as quickly as possible. Case reports can be submitted, but will only be accepted if they are of broad interest to the community and include a systematic review of the literature if possible.
中文简介:(来自Google、百度翻译)
妇产科学档案馆创建于1870年,是“妇科档案馆”,有着悠久而突出的传统。自1922年以来,《华尔街日报》一直是德国格塞尔沙夫特妇科科洛奇和格布尔茨希尔夫的机构,并出版了他们两次年度会议的摘要和会议记录。妇产科档案在全球40多个国家流通,并在现有目录和索引中编入索引。妇产科学档案馆发表“应邀并提交评论”临床专题和基础研究的原始文章、病例报告和“妇产科学各分支学科的初步交流”。所有论文都经过同行评审,并尽快发表。 妇产科档案馆出版 社论 -致编辑的信 新闻与观点 -评论 -关于以下类别的临床主题和基础研究的原始文章: 母胎医学 普通妇科学 妇科肿瘤学 妇科内分泌与生殖医学 泌尿妇科学 -职位声明和指导方针 -对应关系 -妇产科影像学 -勘误表 摘要 来自妇产科的所有分支学科。所有论文都要经过同行评审,并尽快发表。个案报告可以提交,但只有当个案报告引起社会广泛关注,并在可能的情况下包括对文献的系统检讨时,才会获接纳。
ARCHIVES OF GYNECOLOGY AND OBSTETRICS 期刊中科院评价数据
最新中科院分区
大类(学科) | 小类(学科) | 学科排名 |
医学 |
OBSTETRICS & GYNECOLOGY(产科医学和妇科医学) 3区 |
34/82 |
最新公布的期刊年发文量
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
308 | 257 | 51 |
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ARCHIVES OF GYNECOLOGY AND OBSTETRICS 期刊CiteScore评价数据
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引文计数(2018)
文献(2015-2017)
2398次引用
1219篇文献
CiteScore排名
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Obstetrics and Gynecology
|
#47/168
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ARCHIVES OF GYNECOLOGY AND OBSTETRICS 期刊常见问题
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liting7111
研究方向:妇产科
审稿时间: 3个月内 接受率: 中等(50%命中)
妇科肿瘤方向文章,投稿三个月出头,现在under review,两周更新一次状态,催稿两次,这是不是要被拒啊,感觉拖得太久了2020-05-02 -
liting7111
研究方向:妇产科
审稿时间: 3个月内 接受率: 中等(50%命中)
投稿快三个月还在under review,两个月的时候催了一次,编辑回复再等等,真的慢!2019-03-11
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