发表一篇学和医学成像类SCI论文
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Abstract:
:Osteosarcoma (OS), a malignant bone tumor, mainly occurs in adolescents. Cluster of differentiation 133 (CD133) is one of the most common tumor stem cell biomarkers. The prognostic significance of CD133 in OS has been reported, while the conclusions of these study were inconsistent. This study was conducted to investigate the association between CD133 expression and OS. We performed a search using several database including NCBI PubMed, Springer, CNKI, Web of Science and Wanfang for relevant papers about the prognostic value of CD133 on OS published before October 19, 2019. Pooled odds ratio (OR) and 95% CI were used to evaluate the outcomes. Seven reports including 498 OS patients were used for evaluating the association between CD133 positive expression and OS clinicopathological features. CD133 positive expression was not related to the age, gender, tumor size, tumor location and pathological type of OS. The expression of CD133 was significantly associated with high ennecking stage of OS (OR 9.67, 95% CI 5.56-16.80, P < 0.05) and OS local recurrence (OR 3.02, 95% CI 1.84-4.94, P < 0.05). In addition, the expressions of CD133 predict metastasis (OR 7.64, 95% CI 4.93-11.85, P < 0.05). Moreover, this study indicated that CD133 expression was correlated to lower 5-year overall survival in OS with the pooled OR of 5.85 (95% CI 3.30-10.37, P < 0.05). Our reported shown that positive expression of CD133 is significantly correlated with ennecking stage, local recurrence, metastasis and low 5-year overall survival rate of OS patients.
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最新影响因子:5.057 | 期刊ISSN:1591-8890 | CiteScore:2.19 |
出版周期:Quarterly | 是否OA:YES | 出版年份:2001 |
自引率:2.00% | 研究方向:医学-医学:研究与实验 |
出版地区:ITALY |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Clinical and Experimental Medicine publishes reports of clinical and experimental work concerned with the following fields: clinical chemistry, hematology, immunology, oncology and virology. The major criteria for publication will be clarity, experimental soundness and advances in knowledge. Papers containing new clinical or experimental data, or which are likely to contribute to changes in clinical practice or in thinking about a disease will be given priority due to their immediate importance.
临床与实验医学发表临床与实验工作报告,涉及以下领域:临床化学、血液学、免疫学、肿瘤学和病毒学。出版的主要标准将是清晰度、实验的可靠性和知识的进步。包含新的临床或实验数据,或可能有助于改变临床实践或对疾病的思考的论文将被优先考虑,因为它们具有直接的重要性。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
MEDICINE, RESEARCH & EXPERIMENTAL (医学:研究与实验) 3区 |
64/133 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
56 | 48 | 8 |
引文计数(2018)
文献(2015-2017)
389次引用
178篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Biochemistry, Genetics and Molecular Biology
小类(学科):General Biochemistry, Genetics and Molecular Biology
|
#61/187
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研究方向:动物模型
审稿时间: 2个月内 接受率: 一般容易(75%命中)
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影响因子:2.655
ISSN:1520-9512
研究方向:医学-呼吸系统
影响因子:3.427
ISSN:1027-3719
研究方向:医学-传染病学
影响因子:4.09
ISSN:8755-6863
研究方向:医学-呼吸系统
影响因子:5.526
ISSN:1526-0542
研究方向:医学-呼吸系统
影响因子:2.973
ISSN:1472-9792
研究方向:医学-呼吸系统
影响因子:3.289
ISSN:2055-1010
研究方向:PRIMARY HEALTH CARE-RESPIRATORY SYSTEM
影响因子:10.262
ISSN:0012-3692
研究方向:医学-呼吸系统
影响因子:2.339
ISSN:0020-1324
研究方向:医学-呼吸系统
影响因子:102.642
ISSN:2213-2600
研究方向:RESPIRATORY SYSTEM-RESPIRATORY SYSTEM
发表一篇学和医学成像类SCI论文
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