[Ocular syphilis, a re-emergent pathology: Series of 12 patients in one Hospital, 2017].

Abstract:
INTRODUCTION:Syphilis is a sexually transmitted disease. All organs might be affected, but ocular syphilis only occurs in 0.6 percent of patients. We collected all cases of ocular syphilis requiring hospitalization at the University Hospital Center (UHC) in Marseille in 2017. PATIENTS AND METHODS:This was a retrospective monocentric study. The diagnosis of ocular syphilis was based on the combination of ocular inflammation with a positive syphilitic serology. For each patient, sex, age, HIV status, ocular and extraocular symptoms, initial visual acuity, syphilis serology, cerebrospinal fluid (CSF) analysis if done, treatment and clinical response were collected. RESULTS:Ten men and two women, aged 28 to 86 years, were hospitalized. Two patients were HIV-positive. Ophtalmological lesions were heterogeneous the posterior structures were most affected. Anterior uveitis was isolated in one patient. Five patients had extraocular signs with cutaneous and/or mucosal involvement. No patient had neurological symptoms. Diagnosis of neurosyphilis through CSF analysis was definite for one patient, probable for 5 patients and ruled out for 2 patients. Six patients received treatment with penicillin G and six with ceftriaxone. Visual acuity improved in all cases. DISCUSSION:Ophtalmic cases of syphilis have become more frequent over the past few years in France. The diagnosis should be suspected in cases of eye inflammation even in the absence of favourable clinical presentation or anamnesis. Search for HIV co-infection should be systematic. Our study shows that ceftriaxone remains an effective alternative to penicillin G.
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REVUE DE MEDECINE INTERNE
REV MED INTERNE
最新影响因子:0.885 | 期刊ISSN:0248-8663 | CiteScore:0.92 |
出版周期:Monthly | 是否OA:YES | 出版年份:0 |
期刊官方网址:https://www.elsevier.com/journals/la-revue-de-medecine-interne/0248-8663#description
自引率:27.30% | 研究方向:医学-医学:内科 |
出版地区:FRANCE |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Official organ of the SNFMI, la Revue de Médecine Interne, La is one of the very few non Anglo-Saxon scientific journals to be indexed in the most prestigious databases. Exacting scientific accuracy is present in all sections: editorials, original articles, focuses, short communications, etc.Moreover, the ''Journal de l'interniste'' constitutes a valuable interface for all internists.
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SNFMI的官方机构,la Revue de Medecine Interne, la是非盎格鲁-撒克逊人的科学期刊之一,被收录在最负盛名的数据库中。严格的科学准确性存在于所有的部分:社论,原创文章,重点,简短的交流,等等,此外,“国际期刊”构成了一个宝贵的接口,为所有国际记者。
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#81/121
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2 |
大类(学科):Medicine
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#84/128
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