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Abstract:
BACKGROUND:Pleural effusions due to heart failure are associated with a high 1-year mortality. Several hematological parameters have been shown to provide prognostic information in patients with cardiovascular diseases. The objective was to assess whether hematological markers can also provide prognostic information in patients with pleural effusion caused by heart failure. METHODS:This was a retrospective study of patients with pleural effusion due to heart failure who underwent a diagnostic thoracentesis. The hematological parameters evaluated were as follows: neutrophils, lymphocytes, neutrophil-to-lymphocyte ratio, platelet count, platelet-to-lymphocyte ratio, mean platelet volume (MPV), and MPV-to-platelet ratio. Patients were divided into two groups: those who died within 1 year and survivors of more than 1 year. Differences and possible correlations were analyzed with non-parametric tests. Diagnostic values were estimated. Survival analysis was performed using the Kaplan-Meier method. Cox regression analysis was performed to identify independent variables. RESULTS:Twenty five of 55 (45%) patients died within 1-year from thoracentesis. Patients who died in this period were older, aged 83 years (73 - 87, median and interquartile range, IQR) vs. 74 (65 - 82); with lower platelet count: 181 x 103 (140 - 258 x 103) vs. 241 x 103 (198 - 324 x 103); and higher MPV/platelet: 48.1 (34.9 - 75.6) vs. 35.6 (27.1 - 42.9). In the regression analysis only the MPV/platelet had statistical significance (p = 0.002). MPV/platelet > 50 had a specificity of 87% for 1-year mortality, and a ratio > 30 had a sensitivity of 84%. CONCLUSIONS:Simple hematological parameters such as platelet count and MPV/platelet, may provide useful prognostic information for predicting 1-year mortality in patients with pleural effusion due to heart failure.
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最新影响因子:1.053 | 期刊ISSN:1433-6510 | CiteScore:0.94 |
出版周期:Bimonthly | 是否OA:YES | 出版年份:1997 |
自引率:5.20% | 研究方向:医学-医学实验技术 |
出版地区:GERMANY |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Clinical Laboratory is an international fully peer-reviewed journal covering all aspects of laboratory medicine and transfusion medicine. In addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies. The journal publishes original articles, review articles, posters, short reports, case studies and letters to the editor dealing with 1) the scientific background, implementation and diagnostic significance of laboratory methods employed in hospitals, blood banks and physicians' offices and with 2) scientific, administrative and clinical aspects of transfusion medicine and 3) In addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies. Clinical Laboratory provides an international forum for the publication of original articles describing basic, translational and clinical investigation in laboratory medicine and transfusion medicine. In addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies.
《临床实验室》是一份国际上完全经过同行评审的期刊,涵盖了实验室医学和输血医学的所有方面。除了输血医学专题外,临床实验室还代表有关组织移植和造血、细胞和基因治疗的意见书。该杂志刊登原创文章、评论文章、海报、短篇报告、案例研究和给编辑的信件,内容涉及1)医院、血库和医生办公室使用的实验室方法的科学背景、实施和诊断意义,2)科学的,输血医学的行政和临床方面以及3)除了输血医学主题,临床实验室还代表有关组织移植和造血、细胞和基因治疗的意见书。 临床实验室为出版描述实验室医学和输血医学的基础、转化和临床研究的原始文章提供了一个国际论坛。除了输血医学专题外,临床实验室还代表有关组织移植和造血、细胞和基因治疗的意见书。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
MEDICAL LABORATORY TECHNOLOGY (医学实验技术) 4区 |
25/30 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
244 | 233 | 11 |
引文计数(2018)
文献(2015-2017)
817次引用
870篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Biochemistry, Genetics and Molecular Biology
小类(学科):General Biochemistry, Genetics and Molecular Biology
|
#112/187
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研究方向:meta 生物标志物
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影响因子:1.714
ISSN:1386-2073
研究方向:化学-生化研究方法
影响因子:6.088
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研究方向:医学-神经科学
影响因子:1.379
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研究方向:医学-临床神经学
影响因子:4.287
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影响因子:1.821
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ISSN:1178-6973
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影响因子:5.758
ISSN:0305-7453
研究方向:医学-传染病学
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