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Abstract:
:Radiation exposure is among the few factors known to be associated with risk of central nervous system (CNS) tumors. However, the patterns of radiation risk by histological type, sex or age are unclear. We evaluated radiation risks of first primary glioma, meningioma, schwannoma, and other or not otherwise specified (other/NOS) tumors in the Life Span Study cohort of atomic bomb survivors. Cases diagnosed between 1958 and 2009 were ascertained through population-based cancer registries in Hiroshima and Nagasaki. To estimate excess relative risk per Gy (ERR/Gy), we fit rate models using Poisson regression methods. There were 285 CNS tumors (67 gliomas, 107 meningiomas, 49 schwannomas, and 64 other/NOS tumors) among 105,444 individuals with radiation dose estimates to the brain contributing 3.1 million person-years of observation. Based on a simple linear model without effect modification, ERR/Gy was 1.67 (95% confidence interval, CI: 0.12 to 5.26) for glioma, 1.82 (95% CI: 0.51 to 4.30) for meningioma, 1.45 (95% CI: - 0.01 to 4.97) for schwannoma, and 1.40 (95% CI: 0.61 to 2.57) for all CNS tumors as a group. For each tumor type, the dose-response was consistent with linearity and appeared to be stronger among males than among females, particularly for meningioma (P = 0.045). There was also evidence that the ERR/Gy for schwannoma decreased with attained age (P = 0.002). More than 60 years after the bombings, radiation risks for CNS tumors continue to be elevated. Further follow-up is necessary to characterize the lifetime risks of specific CNS tumors following radiation exposure.
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最新影响因子:12.434 | 期刊ISSN:0393-2990 | CiteScore:5.81 |
出版周期:Monthly | 是否OA:YES | 出版年份:1985 |
自引率:12.50% | 研究方向:医学-公共卫生、环境卫生与职业卫生 |
出版地区:NETHERLANDS |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
专业编辑在线一对一答疑及时解决您的问题
European Journal of Epidemiology, published for the first time in 1985, serves as a forum on the epidemiology of communicable and non-communicable diseases and their control. The results of epidemiologic studies are essential arguments for action in the field of public health policies and efforts are made to bring the journal to the decision makers'' attention. The journal is also a source of material for those who are actively engaged in teaching epidemiology. The journal covers the different fields of epidemiology, a science which has always been multidisciplinary by nature: contributions are encouraged from the fields of public health planning and control, economy, preventive medicine, clinical trials, vaccinology, psychology, molecular biology, mathematical modelization and computer sciences.
1985年首次出版的《欧洲流行病学杂志》是关于传染病和非传染病及其控制的流行病学的论坛。流行病学研究的结果是在公共卫生政策领域采取行动的基本论据,并努力使该杂志引起决策者的“注意”。该杂志也是那些积极从事流行病学教学的人的资料来源。该杂志涵盖流行病学的不同领域,这是一门本质上一直是多学科的科学:鼓励来自公共卫生规划和控制、经济、预防医学、临床试验、疫苗学、心理学、分子生物学、数学模型化和计算机科学等领域的贡献。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH (公共卫生、环境卫生与职业卫生) 1区 |
7/181 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
93 | 89 | 4 |
引文计数(2018)
文献(2015-2017)
1888次引用
325篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Epidemiology
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#7/87
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研究方向:流行病学 公共卫生
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影响因子:1.714
ISSN:1386-2073
研究方向:化学-生化研究方法
影响因子:6.088
ISSN:1933-7213
研究方向:医学-神经科学
影响因子:1.379
ISSN:0362-5664
研究方向:医学-临床神经学
影响因子:4.287
ISSN:1473-7175
研究方向:CLINICAL NEUROLOGY-PHARMACOLOGY & PHARMACY
影响因子:1.821
ISSN:1528-4336
研究方向:医学-传染病学
影响因子:2.385
ISSN:1120-009X
研究方向:医学-药学
影响因子:2.706
ISSN:1076-6294
研究方向:医学-传染病学
影响因子:4.177
ISSN:1178-6973
研究方向:-
影响因子:5.758
ISSN:0305-7453
研究方向:医学-传染病学
发表一篇学和医学成像类SCI论文
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