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Abstract:
OBJECTIVES:Current study aimed to find the effects of curcumin on quality of life (QoL) in liver cirrhotic patients. DESIGN:In this randomized double-masked placebo-controlled trial, 70 cases with liver cirrhosis aged 20-70 years were randomly divided into two groups to receive 1000 mg/day curcumin (n = 35) or placebo (n = 35) for 12 weeks. The health-related QoL (HRQoL) was assessed by CLDQ, LDSI 2.0, and SF-36. RESULTS:Fifty-eight patients (28 in curcumin and 30 in placebo groups) finished the research. Compared with baseline, overall scores as well as most of CLDQ domains (e.g. Fatigue, Emotional Function, Worry, Abdominal Symptoms, and Systemic Symptoms) and the Physical and Mental health (Total) scores and most of SF-36 domains (e.g. Physical Functioning, Bodily Pain, Vitality, Social Functioning, and Mental Health) increased considerably (P < 0.05) after curcumin administration. Furthermore, curcumin reduced most of LDSI 2.0 domains (e.g. Itch, Joint pain, Pain in the right upper abdomen, Sleeping during the day, Decreased appetite, Depression, Fear of complication, Jaundice, Hindrance in Financial Affairs, Change in use of time, Decreased sexual interest, and Decreased sexual activity) significantly (P < 0.05). Significant differences were noticed between two groups in CLDQ domains and overall scores, LDSI 2.0 domains and overall scores, SF-36 Physical and Mental health (total) scores and all its domains scores (P < 0.05), adjusting for baseline values and disease duration. CONCLUSIONS:Curcumin improved QoL in liver cirrhotic patients according to CLDQ, LDSI 2.0, and SF-36 domains. Additional studies are warranted to consider curcumin as a safe, accessible, and low-cost complementary therapeutic option in cirrhosis.
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最新影响因子:3.335 | 期刊ISSN:0965-2299 | CiteScore:2.54 |
出版周期:Bimonthly | 是否OA:YES | 出版年份:1993 |
期刊官方网址:http://www.journals.elsevier.com/complementary-therapies-in-medicine/
自引率:6.60% | 研究方向:医学-全科医学与补充医学 |
出版地区:ENGLAND |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Complementary Therapies in Medicine is aimed primarily at health care practitioners including GPs, nurses, physiotherapists and complementary therapists. It publishes a variety of articles - primary research, reviews and opinion pieces - and has considerable appeal to practitioners of conventional or complementary medicine who are seeking objective and critical information on complementary therapies or who wish to deepen their understanding of these approaches.
医学上的补充疗法主要针对卫生保健从业者,包括全科医生、护士、物理治疗师和补充治疗师。它发表各种各样的文章- -初级研究、评论和意见文章- -对正在寻求关于补充疗法的客观和关键信息或希望加深对这些方法的理解的传统或补充医学的从业者具有相当大的吸引力。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
INTEGRATIVE & COMPLEMENTARY MEDICINE (全科医学与补充医学) 3区 |
9/27 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
110 | 86 | 24 |
引文计数(2018)
文献(2015-2017)
923次引用
364篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Health Professions
小类(学科):Complementary and Manual Therapy
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#1/12
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2 |
大类(学科):Medicine
小类(学科):Complementary and Alternative Medicine
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#13/91
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3 |
大类(学科):Nursing
小类(学科):Advanced and Specialized Nursing
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#3/50
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研究方向:医药科学 中医学 中医学其他科学问题
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研究方向:针刺 脑成像
审稿时间: 12个月内 接受率: 中等(50%命中)
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影响因子:2.748
ISSN:0026-1394
研究方向:工程技术-物理:应用
影响因子:1.843
ISSN:0034-6748
研究方向:工程技术-物理:应用
影响因子:2.442
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研究方向:工程技术-光学
影响因子:1.643
ISSN:1768-6733
研究方向:INSTRUMENTS & INSTRUMENTATION-MATERIALS SCIENCE, C
影响因子:1.446
ISSN:0970-3950
研究方向:工程技术-物理:应用
影响因子:8.307
ISSN:2040-3364
研究方向:CHEMISTRY, MULTIDISCIPLINARY-NANOSCIENCE & NANOTEC
影响因子:6.739
ISSN:2191-9089
研究方向:CHEMISTRY, MULTIDISCIPLINARY-NANOSCIENCE & NANOTEC
影响因子:2.838
ISSN:2076-3417
研究方向:CHEMISTRY, MULTIDISCIPLINARYMATERIALS SCIE-MATERIA
影响因子:2.024
ISSN:1745-8080
研究方向:工程技术-材料科学:综合
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COMPLEMENTARY THERAPIES IN MEDICINE 投稿经验
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